Accuracy of transvaginal Doppler ultrasound in differentiating malignant adnexal masses

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Lisette Estefanía Estupiñán-Ramírez
Karla Lissette Loor-García
Nelly Estefanía Cedeño-Cedeño
Viviana Mercedes Bailon-Cedeño
Alberto Alfonso Romero-Vélez

Abstract

Ovarian cancer is associated with high morbidity and mortality because it is asymptomatic in its early stages, making the accurate characterization of adnexal masses a major clinical challenge. To analyze the diagnostic accuracy of transvaginal Doppler ultrasound in distinguishing between benign and malignant adnexal masses.  Methodology: A systematic review was conducted using the PRISMA method, analyzing 26 indexed scientific articles published between 2020 and 2026.  Results: Doppler flowmetry detects abnormal tumor neovascularization, achieving a sensitivity of 91% and a specificity of 88% when combined with standardized reporting systems such as O-RADS and IOTA.  Although interpretation is operator-dependent, the integration of two-dimensional anatomy with hemodynamics allows for accurate risk assessment, thereby avoiding unnecessary radical surgeries for benign masses. Transvaginal Doppler ultrasound is the first-line noninvasive diagnostic tool. Its structured use improves patient survival by optimizing timely referral to a gynecologic oncologist.

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Estupiñán-Ramírez, L. E., Loor-García, K. L., Cedeño-Cedeño, N. E., Bailon-Cedeño, V. M., & Romero-Vélez, A. A. (2026). Accuracy of transvaginal Doppler ultrasound in differentiating malignant adnexal masses. Scientific Journal Science and Method, 4(3), 265-278. https://doi.org/10.55813/gaea/rcym/v4/n3/235

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