Pharmacoeconomic Evaluation of Hospital Pharmacist Interventions to Reduce Healthcare Costsº

Abstract

This study evaluates the pharmacoeconomic impact of hospital pharmacist interventions on the optimization of resources and healthcare investment in the hospital setting. A systematic review based on the PRISMA methodology was conducted, analyzing scientific evidence published between 2020 and 2026 retrieved from high-impact databases such as Scopus, Web of Science, SciELO, Trip Database. The interventions evaluated included medication reconciliation, clinical pharmacokinetic monitoring, optimization of antimicrobial regimens, and sequential conversion from intravenous to oral therapy. The results show that the return on investment ranges from 4.3:1 to 8.5:1 for every dollar invested in clinical pharmacy services, primarily due to the prevention of adverse drug events and the reduction in length of hospital stay. Furthermore, incremental cost-effectiveness analyses demonstrate that these interventions represent dominant strategies compared to standard care. It is concluded that the clinical integration of the pharmaceutical biochemist leads to a significant reduction in healthcare costs and increases patient safety, establishing itself as an essential component of efficiency for the economic sustainability of healthcare institutions.